18 F-FDG accumulation at the early onset of acute exacerbation of idiopathic interstitial pneumonia on 18 F-FDG PET/CT: A case report.
Kimitaka AkaikeKoichi SaruwatariShinya SakataSeitaro OdaShinya ShiraishiShinji IyamaAiko MasunagaYusuke TomitaHidenori IchiyasuTakuro SakagamiPublished in: Respirology case reports (2024)
Acute exacerbation of idiopathic interstitial pneumonias (AE-IIPs) is a disease associated with a poor prognosis in patients with IIPs. However, the specific characteristics of fluorine-18 2-fluoro-2-deoxy-d-glucose ( 18 F-FDG) positron emission tomography/computed tomography (PET/CT) imaging for AE-IIPs remain unclear. Herein, we present the case of a patient with lung cancer combined with IIPs who underwent 18 F-FDG PET/CT at the early onset of AE-IIPs. The scan, conducted 18 days post-bronchoscopy for lung cancer evaluation, revealed AE-IIPs before the onset of respiratory failure. New ground-glass opacities appeared, accompanied by significant 18 F-FDG accumulation extending beyond these regions. To the best of our knowledge, this report represents the first assessment of 18 F-FDG PET/CT images at the early onset of AE-IIPs before respiratory failure in humans. The observed features in this PET image could potentially contribute to our understanding of the pathophysiology of AE-IIPs.
Keyphrases
- positron emission tomography
- early onset
- respiratory failure
- computed tomography
- pet ct
- extracorporeal membrane oxygenation
- late onset
- poor prognosis
- mechanical ventilation
- pet imaging
- magnetic resonance imaging
- long non coding rna
- deep learning
- intensive care unit
- acute respiratory distress syndrome
- healthcare
- high resolution
- chronic obstructive pulmonary disease
- contrast enhanced
- case report
- image quality
- machine learning
- skeletal muscle
- convolutional neural network
- metabolic syndrome
- blood pressure
- hepatitis b virus
- magnetic resonance
- weight loss
- insulin resistance