Alpha2 -receptor agonists as adjuvants for brachial plexus nerve blocks - a systematic review with meta-analyses.

Jakob Hessel Andersen Anders Peder Højer Karlsen Anja GeislerPia JaegerUlrik GrevstadJørgen B DahlOle Mathiesen

Published in: Acta anaesthesiologica Scandinavica (2021)

Alpha2-receptor agonists used as adjuvants for brachial plexus blocks lead to a prolonged duration of analgesia, with dexmedetomidine as the most efficient. Alpha2-receptor agonists were associated with increased risk of cardiovascular adverse events. The quality of evidence was low to very low.

Keyphrases

meta analyses
systematic review
randomized controlled trial
pain management
quality improvement