In vivo PET of synaptic density as potential diagnostic marker for cognitive disorders: prospective comparison with current imaging markers for neuronal dysfunction and relation to symptomatology - study protocol.
Greet VanderlindenCharles CarronRik VandenbergheMathieu VandenbulckeKoen Van LaerePublished in: BMC medical imaging (2024)
F-FDG PET in cognitive disorders with uncertain etiology and in exclusion of a neurodegenerative cause in patients with cognitive impairment in late-life psychiatric disorders. The strength of the relationship between cognition and imaging data will be assessed, as well as the potential incremental diagnostic value of including MR volumetry, ASL perfusion and rs-fMRI.
Keyphrases
- pet ct
- positron emission tomography
- high resolution
- cognitive impairment
- pet imaging
- study protocol
- computed tomography
- randomized controlled trial
- contrast enhanced
- clinical trial
- functional connectivity
- magnetic resonance
- electronic health record
- oxidative stress
- resting state
- big data
- multiple sclerosis
- mild cognitive impairment
- risk assessment
- white matter
- deep learning
- artificial intelligence
- open label
- photodynamic therapy
- climate change
- placebo controlled