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Identification of potential genetic causal variants for obesity-related traits using statistical fine mapping.

Rui GongJonathan GreenbaumXu LinYan DuKuan-Jui SuYun GongJie ShenHong-Wen Deng
Published in: Molecular genetics and genomics : MGG (2023)
Using a statistical fine-mapping approach, we identified a set of potential causal variants to be prioritized for future functional validation and also detected some novel trait-associated variants. These results provided novel insight into our understanding of the genetics of obesity and also demonstrated that fine mapping may improve upon the results identified by the original GWASs.
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