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Therapeutic targeting of SLC6A8 creatine transporter suppresses colon cancer progression and modulates human creatine levels.

Isabel KurthNorihiro YamaguchiCelia Andreu-AgulloHelen S TianSubhasree SridharShugaku TakedaFoster C GonsalvesJia Min LooAfsar BarlasKatia ManovaRobert W BusbyJohanna C BendellJames F StraussMarwan G FakihAutumn J McReeAndrew E HendifarLee S RosenAndrea CercekRobert WassermanMichael SzarekScott L SpectorSyed RazaMasoud F Tavazoie
Published in: Science advances (2021)
[Figure: see text].
Keyphrases
  • endothelial cells
  • induced pluripotent stem cells
  • signaling pathway
  • cancer therapy
  • pluripotent stem cells
  • smoking cessation
  • drug delivery