Analysis of hard tissue regeneration and Wnt signalling in dental pulp tissues after direct pulp capping with different materials.

Kamonwan YaemkleebbuaT OsathanonN NowwaroteC N LimjeerajarusW Sukarawan

Published in: International endodontic journal (2019)

All test materials promoted dentine bridge formation and stimulated cyclin D1 expression. The favourable outcome after direct pulp capping with Biodentine™ involved Wnt/β-catenin signalling. However, Wnt/β-catenin signalling did not participate in the mechanism by which Ca(OH)2 and MTA promoted reparative dentine formation.

Keyphrases

cell proliferation
stem cells
cell cycle
epithelial mesenchymal transition
poor prognosis
gene expression
protein kinase