Potential of Natural Honey in Controlling Obesity and its Related Complications.
Muhammad Faiz ZulkifliMohd Naim Fadhli Mohd RadziJonel P SaludesDoralyn S DalisayWan Iryani Wan IsmailPublished in: Journal of evidence-based integrative medicine (2022)
Honey has a long history of therapeutic properties for multiple diseases, including inflammation and oxidative stress. This review aimed to provide a better understanding and renewed interest in the potential role of honey in obesity control, obesity-related diseases treatment and weight management, with specific reference to its components and the effect of honey overall. There is compelling evidence that honey possesses the desired properties for this purpose, as seen in the in vitro , in silico, in vivo and clinical analyses discussed in this review. This review also highlights the components potentially responsible for the health benefits of honey. Honey and its components reduce blood sugar levels, improve insulin sensitivity and lipid metabolism by reducing triglycerides, and reduce total cholesterol and LDL levels while increasing HDL levels that prevent excessive weight gain and reduce the risk of obesity and its complications. Further controlled studies are necessary to validate the role of honey in the management of obesity, both as a preventive and as a therapeutic agent.
Keyphrases
- weight gain
- weight loss
- body mass index
- insulin resistance
- birth weight
- metabolic syndrome
- oxidative stress
- high fat diet induced
- type diabetes
- adipose tissue
- human health
- ischemia reperfusion injury
- social media
- molecular docking
- health information
- skeletal muscle
- fatty acid
- signaling pathway
- molecular dynamics simulations
- combination therapy