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TARGET OF MONOPTEROS (TMO):A key type of Transcription Factors Orchestrating Plant Development and Environmental Response.

Min ChenYani DaiJiamin LiaoHuan WuQiang LvYu HuangLichang LiuYu FengHongxuan LvBo ZhouDan Peng
Published in: Journal of experimental botany (2024)
Plants have an incredible ability to sustain root and vascular growth after initiation of the embryonic root and the specification of vascular tissue in early embryos. Microarray assays have revealed that a group of transcription factors (TARGET OF MONOPTEROS) are important for embryonic root initiation in Arabidopsis. Despite their discovery of auxin responsiveness early on, their function and mode of action remained unknown for many years. The advent of genome editing has accelerated the study of TMO transcription factors, revealing novel functions for biological processes such as vascular development, root system architecture, and response to environmental cues. This review covers recent achievements in understanding the developmental function and the genetic mode of action of TMO transcription factors in Arabidopsis and other plant species. We highlight the transcriptional and post-transcriptional regulation of TMO transcription factors in relation to their function, mainly in Arabidopsis. Finally, we provide suggestions for further research and possible applications in plant genetic engineering.
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