Association of Low Muscle Density With Deteriorations in Muscle Strength and Physical Functioning in Rheumatoid Arthritis.
Joshua F BakerSogol Mostoufi-MoabJin LongElena TaratutaMary B LeonardBabette ZemelPublished in: Arthritis care & research (2021)
Worsening of skeletal muscle density occurred in patients with higher disease activity, in smokers, and in those with lower IGF-1. Low muscle density was associated with worsening of physical function. Interventions addressing reductions in muscle quality might prevent functional decline.
Keyphrases
- skeletal muscle
- disease activity
- rheumatoid arthritis
- systemic lupus erythematosus
- rheumatoid arthritis patients
- ankylosing spondylitis
- insulin resistance
- physical activity
- juvenile idiopathic arthritis
- interstitial lung disease
- type diabetes
- cell proliferation
- adipose tissue
- idiopathic pulmonary fibrosis
- growth hormone