Fatty Liver Disease in a Prospective North American Cohort of Adults With Human Immunodeficiency Virus and Hepatitis B Virus Coinfection.

Mandana KhaliliWendy C KingDavid E KleinerMamta K JainRaymond T ChungMark SulkowskiMauricio Lisker-MelmanDavid K WongMarc GhanyArun SanyalRichard K Sterling

Published in: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America (2021)

About 30% with HIV-HBV coinfection had FLD including 10% with steatohepatitis. FLD was associated with non-black race, metabolic risks, an atherogenic lipid profile, and elevated ALT over time. Thus, identification of FLD and management of adverse metabolic profiles are critically important in HIV-HBV coinfection. Clinical Trial Registration. NCT01924455.

Keyphrases

hepatitis b virus
human immunodeficiency virus
antiretroviral therapy
hepatitis c virus
hiv infected
hiv positive
clinical trial
liver failure
hiv aids
hiv testing
open label
risk assessment
emergency department
phase ii
double blind
human health
fatty acid