Photochemical Synthesis of 1,4-Dicarbonyl Bifluorene Compounds via Oxidative Radical Coupling Using TEMPO as the Oxygen Atom Donor.

Jincheng XuAishun DingYanbin Zhang Hao Guo

Published in: The Journal of organic chemistry (2021)

A visible-light-induced metal-free synthesis of 1,4-dicarbonyl compounds from alkyne-containing aryl iodides via photochemical C-I bond cleavage, intramolecular cyclization, oxidation, and intermolecular radical coupling sequence is reported. TEMPO was employed as the oxygen atom donor in this transformation. This protocol provided a new strategy for the synthesis of 1,4-dicarbonyl bifluorene compounds.

Keyphrases

electron transfer
molecular dynamics
randomized controlled trial
hydrogen peroxide
energy transfer
dna binding
quantum dots
transition metal