Systematic review and case series: flexible sigmoidoscopy identifies most cases of checkpoint inhibitor-induced colitis.

Andrew P WrightMarc S PiperShrinivas BishuRyan William Stidham

Published in: Alimentary pharmacology & therapeutics (2019)

Moderate to severe checkpoint inhibitor-induced colitis involves the left colon in the majority of cases (>98%). Sigmoidoscopy should be the initial endoscopic procedure in the evaluation of this condition.

Keyphrases

systematic review
dna damage
cell cycle
meta analyses
genome wide
ultrasound guided
early onset
high intensity
randomized controlled trial
dna methylation
endoscopic submucosal dissection