Real-world patient characteristics associated with survival of 2 years or more after radium-223 treatment for metastatic castration-resistant prostate cancer (EPIX study).
Daniel J GeorgeArchana M AgarwalA Oliver SartorCora N SternbergBertrand TombalFred SaadKurt MillerNiculae ConstantinoviciHelen GuoJohn ReevesXiaoLong JiaoPer SandströmFrank VerholenCelestia S HiganoNeal ShorePublished in: Prostate cancer and prostatic diseases (2022)
In this study of men with mCRPC treated in real-world clinical practice, median OS was consistent with that seen in the phase 3 ALSYMPCA trial. Patients who survived ≥2 years after the start of radium-223 were younger and had better ECOG PS, lower disease burden, and less use of prior chemotherapy than those who survived <2 years.