Treatment of severe recalcitrant pyoderma gangrenosum with ustekinumab.
Zhi Mei LowAdrian MarPublished in: The Australasian journal of dermatology (2017)
An increased expression of interleukin-23 has been observed in patients with pyoderma gangrenosum, leading to the use of ustekinumab as a therapeutic option. We report the successful use of ustekinumab in three patients with treatment-resistant pyoderma gangrenosum of varying clinical presentations.