Smoking, body mass index, disease activity, and the risk of rapid radiographic progression in patients with early rheumatoid arthritis.

Emil RydellKristina ForslindJan-Åke NilssonLennart T H JacobssonCarl Turesson

Published in: Arthritis research & therapy (2018)

A history of smoking, presence of RF and/or anti-CCP and early erosions, high initial disease activity and active disease at 1 year, all increase the risk of RRP. Patients with a high BMI may have a reduced risk of severe joint damage. This pattern was not explained by differences in disease activity or antibody status. The results of this study suggest independent effects of smoking and BMI on the risk of RRP.

Keyphrases

disease activity
rheumatoid arthritis
body mass index
systemic lupus erythematosus
rheumatoid arthritis patients
smoking cessation
ankylosing spondylitis
weight gain
juvenile idiopathic arthritis
physical activity
oxidative stress
early onset
loop mediated isothermal amplification
sensitive detection