Neonatal Caffeine Treatment and Respiratory Function at 11 Years in Children under 1,251 g at Birth.
Lex William DoyleSarath RanganathanJeanie Ling Yoong CheongPublished in: American journal of respiratory and critical care medicine (2017)
Caffeine treatment in the newborn period improves expiratory flow rates in midchildhood, which seems to be achieved by improving respiratory health in the newborn period. Follow-up lung function testing in adulthood is vital for these individuals. Future placebo-controlled randomized trials of neonatal caffeine are unlikely. Clinical trial registered with www.clinicaltrials.gov (NCT00182312).
Keyphrases
- lung function
- clinical trial
- healthcare
- public health
- chronic obstructive pulmonary disease
- cystic fibrosis
- double blind
- air pollution
- young adults
- placebo controlled
- randomized controlled trial
- mental health
- depressive symptoms
- study protocol
- pregnant women
- risk assessment
- squamous cell carcinoma
- phase iii
- combination therapy
- open label
- social media
- preterm birth
- mechanical ventilation
- gestational age
- rectal cancer