Differentiation of adipose-derived stem cells to functional CD105neg CD73low melanocyte precursors guided by defined culture condition.
Gabriela ZavalaCarolina SandovalDaniel MezaRafael ContrerasWalter GubelinMaroun KhouryPublished in: Stem cell research & therapy (2019)
This study proposes a rapid and scalable protocol for the generation of proliferative melanocyte precursors (PreMel) from ADSC. These PreMel display the essential functional characteristics of bona fide HEM, opening a new path for an autologous cellular therapy for vitiligo patients.