PCSK9 is Increased in Cerebrospinal Fluid of Individuals With Alcohol Use Disorder.

Ji Soo LeeDaniel RosoffAudrey LuoMartha LongleyMonte PhillipsKatrin CharletChristine MuenchJeesun JungFalk W Lohoff

Published in: Alcoholism, clinical and experimental research (2019)

Our data suggest that PCSK9 is elevated in the CSF of individuals with AUD, which may indicate a potential role of PCSK9 in AUD. Additional studies are necessary to further elucidate the functions of PCSK9 in the brain.

Keyphrases

alcohol use disorder
cerebrospinal fluid
low density lipoprotein
electronic health record
resting state
big data
functional connectivity
data analysis