Falk W Lohoff

Publication Activity (10 Years)

Years Active: 2018-2024
Publications (10 Years): 24

Top Topics

Dna Methylation

Genome Wide Association Study

Alcohol Use Disorder

Drosophila Melanogaster

Top Venues

Circulation. Genomic and precision medicine

Alcohol, clinical & experimental research

Alcoholism, clinical and experimental research

Addiction biology

This page only lists publications with an associated author ORCID identifier.

Publications

Daniel B Rosoff, Andrew S Bell, Lucas A Mavromatis, Ali Hamandi, Lauren Park, Jeesun Jung, Josephin Wagner, Pal Pacher, David W Ray, George Davey Smith, Falk W Lohoff
Evaluating the Cardiovascular Impact of Genetically Proxied PCSK9 and HMGCR Inhibition in East Asian and European Populations: A Drug-Target Mendelian Randomization Study. Circulation. Genomic and precision medicine 17 (1) (2024)
Daniel B Rosoff, Andrew S Bell, Lucas A Mavromatis, Ali Hamandi, Lauren Park, Jeesun Jung, Josephin Wagner, Pal Pacher, David W Ray, George Davey Smith, Falk W Lohoff
Evaluating the Cardiovascular Impact of Genetically Proxied PCSK9 and HMGCR Inhibition in East Asian and European Populations: A Drug-Target Mendelian Randomization Study. Circulation. Genomic and precision medicine 17 (1) (2024)
Lea Zillich, Metin Cetin, Elisabeth M Hummel, Eric Poisel, Gabriel R Fries, Josef Frank, Fabian Streit, Jerome Clifford Foo, Lea Sirignano, Marion M Friske, Bernd Lenz, Sabine Hoffmann, Kristina Adorjan, Falk Kiefer, Georgy Bakalkin, Anita C Hansson, Falk W Lohoff, Olli Kärkkäinen, Eloise Kok, Pekka J Karhunen, Greg T Sutherland, Consuelo Walss-Bass, Rainer Spanagel, Marcella Rietschel, Dirk A Moser, Stephanie H Witt
Biological aging markers in blood and brain tissue indicate age acceleration in alcohol use disorder. Alcohol, clinical & experimental research 48 (2) (2024)
Lea Zillich, Metin Cetin, Elisabeth M Hummel, Eric Poisel, Gabriel R Fries, Josef Frank, Fabian Streit, Jerome Clifford Foo, Lea Sirignano, Marion M Friske, Bernd Lenz, Sabine Hoffmann, Kristina Adorjan, Falk Kiefer, Georgy Bakalkin, Anita C Hansson, Falk W Lohoff, Olli Kärkkäinen, Eloise Kok, Pekka J Karhunen, Greg T Sutherland, Consuelo Walss-Bass, Rainer Spanagel, Marcella Rietschel, Dirk A Moser, Stephanie H Witt
Biological aging markers in blood and brain tissue indicate age acceleration in alcohol use disorder. Alcohol, clinical & experimental research 48 (2) (2024)
Daniel B Rosoff, Andrew S Bell, Lucas A Mavromatis, Ali Hamandi, Lauren Park, Jeesun Jung, Josephin Wagner, Pal Pacher, David W Ray, George Davey Smith, Falk W Lohoff
Evaluating the Cardiovascular Impact of Genetically Proxied PCSK9 and HMGCR Inhibition in East Asian and European Populations: A Drug-Target Mendelian Randomization Study. Circulation. Genomic and precision medicine 17 (1) (2024)
Daniel B Rosoff, Andrew S Bell, Lucas A Mavromatis, Ali Hamandi, Lauren Park, Jeesun Jung, Josephin Wagner, Pal Pacher, David W Ray, George Davey Smith, Falk W Lohoff
Evaluating the Cardiovascular Impact of Genetically Proxied PCSK9 and HMGCR Inhibition in East Asian and European Populations: A Drug-Target Mendelian Randomization Study. Circulation. Genomic and precision medicine 17 (1) (2024)
Lea Zillich, Metin Cetin, Elisabeth M Hummel, Eric Poisel, Gabriel R Fries, Josef Frank, Fabian Streit, Jerome Clifford Foo, Lea Sirignano, Marion M Friske, Bernd Lenz, Sabine Hoffmann, Kristina Adorjan, Falk Kiefer, Georgy Bakalkin, Anita C Hansson, Falk W Lohoff, Olli Kärkkäinen, Eloise Kok, Pekka J Karhunen, Greg T Sutherland, Consuelo Walss-Bass, Rainer Spanagel, Marcella Rietschel, Dirk A Moser, Stephanie H Witt
Biological aging markers in blood and brain tissue indicate age acceleration in alcohol use disorder. Alcohol, clinical & experimental research 48 (2) (2024)
Daniel B Rosoff, Andrew S Bell, Lucas A Mavromatis, Ali Hamandi, Lauren Park, Jeesun Jung, Josephin Wagner, Pal Pacher, David W Ray, George Davey Smith, Falk W Lohoff
Evaluating the Cardiovascular Impact of Genetically Proxied PCSK9 and HMGCR Inhibition in East Asian and European Populations: A Drug-Target Mendelian Randomization Study. Circulation. Genomic and precision medicine (2024)
Lea Zillich, Metin Cetin, Elisabeth M Hummel, Eric Poisel, Gabriel R Fries, Josef Frank, Fabian Streit, Jerome Clifford Foo, Lea Sirignano, Marion M Friske, Bernd Lenz, Sabine Hoffmann, Kristina Adorjan, Falk Kiefer, Georgy Bakalkin, Anita C Hansson, Falk W Lohoff, Olli Kärkkäinen, Eloise Kok, Pekka J Karhunen, Greg T Sutherland, Consuelo Walss-Bass, Rainer Spanagel, Marcella Rietschel, Dirk A Moser, Stephanie H Witt
Biological aging markers in blood and brain tissue indicate age acceleration in alcohol use disorder. Alcohol, clinical & experimental research (2024)
Daniel B Rosoff, Lucas A Mavromatis, Andrew S Bell, Josephin Wagner, Jeesun Jung, Riccardo E Marioni, George Davey Smith, Steve Horvath, Falk W Lohoff
Multivariate genome-wide analysis of aging-related traits identifies novel loci and new drug targets for healthy aging. Nature aging (2023)
Lucas A Mavromatis, Daniel B Rosoff, Andrew S Bell, Jeesun Jung, Josephin Wagner, Falk W Lohoff
Multi-omic underpinnings of epigenetic aging and human longevity. Nature communications 14 (1) (2023)
Vipavee Niemsiri, Sara Brin Rosenthal, Caroline M Nievergelt, Adam X Maihofer, Maria C Marchetto, Renata Santos, Tatyana Shekhtman, Ney Alliey-Rodriguez, Amit Anand, Yokesh Balaraman, Wade H Berrettini, Holli Bertram, Katherine E Burdick, Joseph R Calabrese, Cynthia V Calkin, Carla Conroy, William H Coryell, Anna DeModena, Lisa T Eyler, Scott Feeder, Carrie Fisher, Nicole Frazier, Mark A Frye, Keming Gao, Julie S Garnham, Elliot S Gershon, Fernando S Goes, Toyomi Goto, Gloria J Harrington, Petter Jakobsen, Masoud Kamali, Marisa Kelly, Susan G Leckband, Falk W Lohoff, Michael J McCarthy, Melvin G McInnis, David Craig, Caitlin E Millett, Francis Mondimore, Gunnar Morken, John I Nurnberger, Claire O' Donovan, Ketil J Øedegaard, Kelly Ryan, Martha Schinagle, Paul D Shilling, Claire Slaney, Emma K Stapp, Andrea Stautland, Bruce Tarwater, Peter P Zandi, Martin Alda, Kathleen M Fisch, Fred H Gage, John R Kelsoe
Focal adhesion is associated with lithium response in bipolar disorder: evidence from a network-based multi-omics analysis. Molecular psychiatry (2023)
Lea Zillich, Josephin Wagner, Rachel H McMahan, Lauren M Park, Colin Hodgkinson, Elizabeth J Kovacs, Falk W Lohoff
Multi-omics analysis of alcohol effects on the liver in young and aged mice. Addiction biology 28 (12) (2023)
Jeesun Jung, Daniel L McCartney, Josephin Wagner, Daniel B Rosoff, Melanie L Schwandt, Hui Sun, Corinde E Wiers, Luana Martins de Carvalho, Nora D Volkow, Rosie M Walker, Archie I Campbell, David J Porteous, Andrew M McIntosh, Riccardo E Marioni, Steve Horvath, Kathryn L Evans, Falk W Lohoff
Alcohol use disorder is associated with DNA methylation-based shortening of telomere length and regulated by TESPA1: implications for aging. Molecular psychiatry 27 (9) (2022)
Andrew S Bell, Daniel B Rosoff, Lucas A Mavromatis, Jeesun Jung, Josephin Wagner, Falk W Lohoff
Comparing the Relationships of Genetically Proxied PCSK9 Inhibition With Mood Disorders, Cognition, and Dementia Between Men and Women: A Drug-Target Mendelian Randomization Study. Journal of the American Heart Association 11 (21) (2022)
Daniel B Rosoff, Joyce Yoo, Falk W Lohoff
Smoking is significantly associated with increased risk of COVID-19 and other respiratory infections. Communications biology 4 (1) (2021)
Martha J Longley, Jisoo Lee, Jeesun Jung, Falk W Lohoff
Epigenetics of alcohol use disorder-A review of recent advances in DNA methylation profiling. Addiction biology 26 (6) (2021)
Falk W Lohoff, Toni-Kim Clarke, Zachary A Kaminsky, Rosie M Walker, Mairead L Bermingham, Jeesun Jung, Stewart W Morris, Daniel Rosoff, Archie I Campbell, Miruna Barbu, Katrin Charlet, Mark James Adams, Jisoo Lee, Andrew M McIntosh, Emma M O'Connell, Heather C Whalley, David J Porteous, Andrew M McIntosh, Kathryn L Evans
Epigenome-wide association study of alcohol consumption in N = 8161 individuals and relevance to alcohol use disorder pathophysiology: identification of the cystine/glutamate transporter SLC7A11 as a top target. Molecular psychiatry (2021)
Daniel B Rosoff, Zachary A Kaminsky, Andrew M McIntosh, George Davey Smith, Falk W Lohoff
Educational attainment reduces the risk of suicide attempt among individuals with and without psychiatric disorders independent of cognition: a bidirectional and multivariable Mendelian randomization study with more than 815,000 participants. Translational psychiatry 10 (1) (2020)
Daniel B Rosoff, George Davey Smith, Nehal Mehta, Toni-Kim Clarke, Falk W Lohoff
Evaluating the relationship between alcohol consumption, tobacco use, and cardiovascular disease: A multivariable Mendelian randomization study. PLoS medicine 17 (12) (2020)
Annika Rosenthal, Anne Beck, Evangelos Zois, Sabine Vollstädt-Klein, Henrik Walter, Falk Kiefer, Falk W Lohoff, Katrin Charlet
Volumetric Prefrontal Cortex Alterations in Patients With Alcohol Dependence and the Involvement of Self-Control. Alcoholism, clinical and experimental research 43 (12) (2019)
Ji Soo Lee, Daniel Rosoff, Audrey Luo, Martha Longley, Monte Phillips, Katrin Charlet, Christine Muench, Jeesun Jung, Falk W Lohoff
PCSK9 is Increased in Cerebrospinal Fluid of Individuals With Alcohol Use Disorder. Alcoholism, clinical and experimental research 43 (6) (2019)
Christine Muench, Katrin Charlet, Nicholas L Balderston, Christian Grillon, Markus Heilig, Carlos R Cortes, Reza Momenan, Falk W Lohoff
Fear conditioning and extinction in alcohol dependence: Evidence for abnormal amygdala reactivity. Addiction biology 26 (1) (2019)
Ji Soo Lee, Jill L Sorcher, Allison D Rosen, Ruslan Damadzic, Hui Sun, Melanie Schwandt, Markus Heilig, John Kelly, Kelsey L Mauro, Audrey Luo, Daniel Rosoff, Christine Muench, Jeesun Jung, Zachary A Kaminsky, Falk W Lohoff
Genetic Association and Expression Analyses of the Phosphatidylinositol-4-Phosphate 5-Kinase (PIP5K1C) Gene in Alcohol Use Disorder-Relevance for Pain Signaling and Alcohol Use. Alcoholism, clinical and experimental research 42 (6) (2018)