Clostridium perfringens antigens and challenges for development of vaccines against necrotic enteritis in poultry.
Stefanie Bressan WallerCleideanny Cancela GalvãoRafael Rodrigues RodriguesCleiderson de Lima AguirresPedro Henrique Dala Nora QuatrinMariliana Luiza Ferreira AlvesMarcos Roberto Alves FerreiraFabricio Rochedo ConceiçãoPublished in: Anaerobe (2024)
An ideal NE vaccine should incorporate multiple antigens, molecular adjuvants, and delivery systems via in ovo and oral routes. The review underscores the challenges in developing and validating NE vaccines and the urgent need for a standardized protocol to replicate aggressive challenges accurately.