Conducting clinical trials in sub-Saharan Africa: challenges and lessons learned from the Malawi Cryptosporidium study.
Neema TotoElaine DouglasMarkus GmeinerLynn K BarrettRobert LindbladLumbani MakhazaWilfred NediJacob PhulusaGerald V QuinnanLeigh A SawyerHerbert TholeWesley C Van VoorhisPui-Ying Iroh TamPublished in: Trials (2020)
This study demonstrated that initiating and implementing human experimental trials in sub-Saharan Africa can be challenging. However, solutions exist and successful execution requires careful planning, ongoing evaluation, responsiveness to new developments, and oversight of all trial operations.