Astilbe chinensis Modulates Platelet Function via Impaired MAPK and PLCγ2 Expression.

Bo-Ra JeonMuhammad IrfanSeung Eun LeeJeong Hoon LeeMan Hee Rhee

Published in: Evidence-based complementary and alternative medicine : eCAM (2018)

A. chinensis extract inhibited platelet aggregation and granule secretion and attenuated GPVI downstream signaling, indicating the potential therapeutic effects of this plant extract on the cardiovascular system and platelet function. We suggest that given plant extract may be a potent candidate to treat platelet-related CVDs and to be used as antiplatelet agent.

Keyphrases

oxidative stress
anti inflammatory
poor prognosis
signaling pathway
cell proliferation
binding protein
long non coding rna
cell wall