CuCl 2 -Catalyzed α-Chloroketonation of Aromatic Alkenes via Visible-Light-Induced LMCT.

Xing-Xian HeHuan-Huan ChangYing-Xue ZhaoXiang-Jie LiSheng-An LiuZhong-Lin ZangCheng-He Zhou Gui-Xin Cai

Published in: Chemistry, an Asian journal (2022)

Here we report a copper-catalyzed protocol for the synthesis of α-chloroketones from aromatic alkenes including electron-deficient olefins under visible-light irradiation. Preliminary mechanistic studies show that the peroxo Cu(II) species is the key intermediate and hydroperoxyl (HOO⋅) and chlorine (Cl⋅) radicals can be generated by ligand-to-metal charge transfer (LMCT).

Keyphrases

visible light
amino acid
randomized controlled trial
drinking water
room temperature
metal organic framework
solar cells
aqueous solution
transition metal