An experimental method to correct low-frequency concentric artifacts in photon counting CT.

Large-area photon counting detectors (PCDs) are usually built by tiling multiple semiconductor panels that often have slightly different spectral responses to input x-rays. As a result of this spectral inconsistency, experimental PCD-CT images of large, human-sized objects may show high-frequency ring artifacts and low-frequency band artifacts. Due to the much larger width of the bands compared with the rings, the concentric artifact problem in PCD-CT images of human-sized objects cannot be adequately addressed by conventional CT ring correction methods. This work presents an experimental method to correct the concentric artifacts in PCD-CT. The method is applicable to not only energy-discriminating PCDs with multiple bins but also PCDs with only a single threshold controller. Its principle is similar to the two-step beam hardening correction method, except that the proposed method uses pixel-specific polynomial functions to address the spectral inconsistency problem across the detector plane. The pixel-specific polynomial coefficients were experimentally calibrated using 15 acrylic sheets and 6 aluminum sheets of known thicknesses. The pixel-specific polynomial functions were used to convert the measured PCD-CT projection data to acrylic- and aluminum-equivalent thicknesses that are energy-independent. The proposed method was experimentally evaluated using a human cadaver head and multiple physical phantoms: two of them contain iodine and one phantom contains dual K-edge contrast materials (gadolinium and iodine). The results show that the proposed method can effectively remove the low-frequency concentric artifacts in PCD-CT images while reducing beam hardening artifacts. In contrast, the conventional CT ring correction algorithm did not adequately address the low-frequency band artifacts. Compared with the direct material decomposition-based correction method, the proposed method not only relaxes the requirement of multi-energy bins but also generates images with lower noise and fewer concentric artifacts.