2-Mercaptoethanol protects against DNA double-strand breaks after kidney ischemia and reperfusion injury through GPX4 upregulation.
Daeun MoonBabu J PadanilamHee-Seong JangJinu KimPublished in: Pharmacological reports : PR (2022)
We have demonstrated that exogenous 2-ME protects against DNA double-strand breaks after kidney IRI through GPX4 upregulation and ATM activation.