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Digital Image Analysis of Ki-67 Stained Tissue Microarrays and Recurrence in Tamoxifen-Treated Breast Cancer Patients.

Nina Gran EgelandKristin JonsdottirKristina Lystlund LauridsenIvar SkalandCathrine Fonnesbech HjorthEinar G GudlaugssonStephen Jacques Hamilton-DutoitTimothy L LashDeirdre P Cronin-FentonEmilius A M Janssen
Published in: Clinical epidemiology (2020)
Our findings suggest that Ki-67 digital image analysis in TMAs is not associated with increased risk of recurrence among tamoxifen-treated ER-positive breast cancer or ER-negative breast cancer patients. Overall, our findings do not support an increased risk of recurrence associated with Ki-67 expression.
Keyphrases
  • positive breast cancer
  • estrogen receptor
  • breast cancer cells
  • free survival
  • neoadjuvant chemotherapy
  • poor prognosis
  • endoplasmic reticulum
  • squamous cell carcinoma
  • lymph node
  • newly diagnosed
  • binding protein