Characterization of tumor-associated macrophages in prostate cancer transgenic mouse models.
Amber E de GrootKayla V Myers ChenTimothy E G KruegerAshley L KiemenNatalia H NagyAlexandria BrameVicente E TorresZhongyuan ZhangLevent TrabzonluW Nathaniel BrennenDenis WirtzAngelo M De MarzoSarah R AmendKenneth J PientaPublished in: The Prostate (2021)
The macrophage density and the adenocarcinoma cancer subtype of Hi-Myc appear to better mirror patient tumors, suggesting that the Hi-Myc model is the more appropriate in vivo TG model for studying TAMs and TME-targeted therapies.