Secreted clusterin inhibits tumorigenesis by modulating tumor cells and macrophages in human meningioma.

Chao KeBoya HuangJian XiangJinlian LiangGuangjie WuMinghui QiuKai ChengLipeng MaoWen LeiYang HuXiaogen TangYizhen TianGuobing ChenOscar Junhong LuoHongyi Zhang

Published in: Neuro-oncology (2024)

CLU might be a key brake of meningioma malignance by synchronously modulating tumor cells and their microenvironment. Our work provides comprehensive insights into meningioma malignancy and a potential therapeutic strategy.

Keyphrases

optic nerve
endothelial cells
signaling pathway
stem cells
pluripotent stem cells