Expression of epithelial growth factors and of apoptosis-regulating proteins, and presence of CD57+ cells in the development of inflammatory periapical lesions.

Walter Arthur Silva ValenteDéborah BarrocasLuciana Armada Fábio Ramoa Pires

Published in: Journal of applied oral science : revista FOB (2022)

More frequent EGF and KGF expression in PCs and the greater presence of CD57+ cells in lesions with intense inflammatory infiltrates suggest that these factors influence IPL development. The greater KGF expression in initial PCs suggests its importance for the initial stages of PC formation.

Keyphrases

cell cycle arrest
poor prognosis
induced apoptosis
oxidative stress
endoplasmic reticulum stress
cell death
binding protein
long non coding rna
pi k akt
signaling pathway
growth factor
cell proliferation
nk cells