Whole Exome Sequencing of Thymoma Patients Exhibiting Exceptional Responses to Pemetrexed Monotherapy.
Tomohiro TanakaYasushi GotoMasafumi HorieKen MasudaYuki ShinnoYuji MatsumotoYusuke OkumaTatsuya YoshidaHidehito HorinouchiNoriko MotoiYasushi YatabeShunichi WatanabeNoboru YamamotoYuichiro OhePublished in: Cancers (2023)
Exceptional responders to pemetrexed for metastatic thymomas may be characterized by arm-level CNVs. Further, whole-genome and RNA sequencing studies should be performed.
Keyphrases
- small cell lung cancer
- end stage renal disease
- newly diagnosed
- ejection fraction
- chronic kidney disease
- squamous cell carcinoma
- advanced non small cell lung cancer
- single cell
- peritoneal dialysis
- prognostic factors
- randomized controlled trial
- clinical trial
- combination therapy
- case control
- tyrosine kinase
- myasthenia gravis