Effect of redundant clinical trials from mainland China evaluating statins in patients with coronary artery disease: cross sectional study.
Yuanxi JiaJiajun WenRiaz QureshiStephan EhrhardtDavid D CelentanoXin WeiLori RosmanYumeng WenKaren A RobinsonPublished in: BMJ (Clinical research ed.) (2021)
Of more than 2000 redundant clinical trials on statins in patients with coronary artery disease identified from mainland China, an extra 3000 MACEs, including nearly 600 deaths, were experienced by participants not treated with statins in these trials. The scale of redundancy necessitates urgent reform to protect patients.