Multicenter, Phase 1, Open Prospective Trial of Gastric Electrical Stimulation for the Treatment of Obesity: First-in-Human Results with a Novel Implantable System.
Givan F PaulusM van AvesaatS van RijnA M E AlleleynJ M SwainT L AbellD B WilliamsN D BouvyA A M MascleePublished in: Obesity surgery (2021)
Gastric electrical stimulation with the Exilis™ system can be considered as safe. No significant effect on food intake, gastric emptying, or gastric motility was observed. The reduction in weight loss with Exilis™ GES was significant but short lasting. Further electrophysiological research is needed to gain more insight in optimal stimulation parameters and lead localization.
Keyphrases
- weight loss
- spinal cord injury
- bariatric surgery
- type diabetes
- insulin resistance
- metabolic syndrome
- study protocol
- randomized controlled trial
- adipose tissue
- gastric bypass
- roux en y gastric bypass
- pseudomonas aeruginosa
- cystic fibrosis
- staphylococcus aureus
- biofilm formation
- skeletal muscle
- physical activity
- smoking cessation
- open label
- replacement therapy
- obese patients