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Distinct immune regulatory receptor profiles linked to altered monocyte subsets in sarcoidosis.

Simon D FraserMichael G CrooksPaul M KayeSimon Paul Hart
Published in: ERJ open research (2021)
Nonclassical monocytes, which are expanded in sarcoidosis, express very low levels of regulatory receptors. Two distinct and persistent phenotypes of CD200R expression in classical and intermediate monocytes could be evaluated as sarcoidosis biomarkers.
Keyphrases
  • peripheral blood
  • dendritic cells
  • transcription factor
  • poor prognosis
  • immune response