Use of bioreactors for culturing human retinal organoids improves photoreceptor yields.
Patrick Ovando-RocheEmma L WestMatthew J BranchRobert D SampsonMilan FernandoPeter MunroAnastasios GeorgiadisMatteo RizziMagdalena KlocArifa NaeemJoana RibeiroAlexander J SmithAnai Gonzalez-CorderoRobin R AliPublished in: Stem cell research & therapy (2018)
Bioreactors represent a promising platform for scaling up the manufacture of retinal cells for use in disease modelling, drug screening and cell transplantation studies.
Keyphrases
- optical coherence tomography
- diabetic retinopathy
- induced apoptosis
- wastewater treatment
- induced pluripotent stem cells
- cell therapy
- endothelial cells
- optic nerve
- cell cycle arrest
- single cell
- high throughput
- pluripotent stem cells
- oxidative stress
- case control
- emergency department
- cell death
- signaling pathway
- stem cells
- mesenchymal stem cells
- drug induced
- adverse drug
- pi k akt