Congenital lipoid adrenal hyperplasia: Immunohistochemical study of testosterone synthesis in Leydig cells.

Kanako MatsuokaYuichi SatoSeiji HoshiTomoyuki KoguchiSoichiro OgawaTomohiro IshiiNobuhiro HagaTomonobu HasegawaYoshiyuki Kojima

Published in: IJU case reports (2020)

The results indicated transcription of testosterone-synthesizing enzymes remained despite lipid accumulation in this patient. The pattern of expression of testosterone-synthesizing enzymes suggested fetal Leydig cells may have remained after birth in the testes of this patient.

Keyphrases

induced apoptosis
cell cycle arrest
replacement therapy
case report
poor prognosis
endoplasmic reticulum stress
cell death
oxidative stress
pregnant women
binding protein
pi k akt