Serum Levels of Infliximab and Anti-Infliximab Antibodies in Brazilian Patients with Crohn's Disease.

Luis Eduardo Miani GomesFrancesca Aparecida Ramos da SilvaLívia Bitencourt PascoalRenato Lazarin RicciGuilherme NogueiraMichel Gardere CamargoMaria de Lourdes Setsuko AyrizonoJoão José FagundesRaquel Franco Leal

Published in: Clinics (Sao Paulo, Brazil) (2019)

The undetectable levels of IFX correlated with the detection of ATIs, which was independent of disease activity. Immunogenicity was not the main factor for the loss of response to IFX in our study, and the majority of patients in both groups (CDA and CDR) had supratherapeutic levels of IFX.

Keyphrases

disease activity
systemic lupus erythematosus
rheumatoid arthritis
end stage renal disease
rheumatoid arthritis patients
ankylosing spondylitis
newly diagnosed
peritoneal dialysis
ulcerative colitis
prognostic factors
loop mediated isothermal amplification