Genomic Mapping of Epidermal Growth Factor Receptor and Mesenchymal-Epithelial Transition-Up-Regulated Tumors Identifies Novel Therapeutic Opportunities.
Lucía Paniagua-HerranzBernard DogerCristina Díaz-TejeiroAdrian SanvicenteCristina Nieto-JiménezVictor MorenoPedro Pérez SeguraGyorffy BalazsEmiliano CalvoAlberto OcañaPublished in: Cancers (2023)
The authors identified tumor types where EGFR and MET were highly expressed and correlated with a high expression of PD-L1, opening the door for the future combination of bi-specific EGFR/MET antibodies with anti-PD(L)1 inhibitors.