Integrative Genomic Analysis of Gemcitabine Resistance in Pancreatic Cancer by Patient-derived Xenograft Models.

Gang YangWenfang GuanZhe CaoWenbo GuoGuangbing XiongFangyu ZhaoMengyu FengJiangdong QiuYueze LiuMichael Q ZhangLei YouTaiping ZhangYupei ZhaoJin Gu

Published in: Clinical cancer research : an official journal of the American Association for Cancer Research (2021)

This integrative genomic study systematically investigated the predictive markers and molecular mechanisms of chemoresistance in pancreatic cancer and provides potential therapy targets for overcoming gemcitabine resistance.

Keyphrases

locally advanced
network analysis
squamous cell carcinoma
radiation therapy
gene expression
mesenchymal stem cells
climate change
human health
cell therapy
genome wide