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Effect of intra-arrest transport, extracorporeal cardiopulmonary resuscitation and immediate invasive assessment in refractory out-of-hospital cardiac arrest: a long-term follow-up of the Prague OHCA trial.

Daniel RobKlaudia FarkasovskaMarketa KreckovaOndrej SmidPetra KavalkovaJaromir MacounMichal HuptychPetra HavrankovaJuraj GalloJan PudilMilan DusikStepan HavranekAles LinhartJan Belohlávek
Published in: Critical care (London, England) (2024)
Among patients with refractory OHCA, the ECPR-based approach significantly improved long-term survival. There were no differences in the neurological outcome, major cardiovascular events and quality of life between the groups, but the trial was possibly underpowered to detect a clinically relevant difference in these outcomes. Trial registration ClinicalTrials.gov Identifier: NCT01511666, Registered 19 January 2012.
Keyphrases
  • cardiopulmonary resuscitation
  • cardiovascular events
  • cardiac arrest
  • phase iii
  • study protocol
  • phase ii
  • clinical trial
  • coronary artery disease
  • randomized controlled trial
  • open label
  • type diabetes
  • skeletal muscle