Comparative analysis of single-cell transcriptomics in human and Zebrafish oocytes.

Handan CanSree K ChanumoluElena Gonzalez-MuñozSukumal PrukudomHasan H OtuJose B Cibelli

Published in: BMC genomics (2020)

Orthologous genes are concurrently highly expressed in the oocytes of the two organisms and these genes belong to similar functional categories. Our results provide evidence that zebrafish could serve as a valid model organism to study the oocyte with direct implications in human.

Keyphrases

single cell
endothelial cells
genome wide
induced pluripotent stem cells
rna seq
pluripotent stem cells
bioinformatics analysis
gene expression
genome wide analysis