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Assessing Outcomes in Patients With Multiple Myeloma Postautologous Stem Cell Transplantation: Contrasting the Effects of Melphalan Dosages at 200 mg/m 2 versus 140 mg/m 2 .

Zachary BrownCampbell ScottLi Fang ZhangRamses SadekAndrea ClarkeAnand JillellaAmany R KeruakousAmber B Clemmons
Published in: Clinical lymphoma, myeloma & leukemia (2024)
Reduced doses melphalan showed no differences in safety or efficacy outcomes versus standard dose even when analyzed based on age and renal function. Larger randomized controlled trials need to be performed to validate these findings.
Keyphrases
  • high dose
  • stem cell transplantation
  • multiple myeloma
  • randomized controlled trial
  • low dose
  • clinical trial
  • type diabetes
  • adipose tissue
  • metabolic syndrome
  • study protocol
  • insulin resistance