An Unusual Case of an ALK-Negative Epithelioid Fibrous Histiocytoma in the External Auditory Canal.

Morgan Leff Alexandra E QuimbyEric MorganJason A Brant

Published in: The Laryngoscope (2024)

This article represents the first reported case in the external auditory canal of epithelioid fibrous histiocytoma (EFH), a rare benign cutaneous epithelioid neoplasm. Immunostaining revealed uncommon negative staining for anaplastic lymphoma kinase (ALK) expression. This case and literature review outline the diagnostic strategy for this highly unusual neoplasm. Laryngoscope, 134:3371-3373, 2024.

Keyphrases

working memory
low grade
advanced non small cell lung cancer
poor prognosis
hearing loss
case report
diffuse large b cell lymphoma
single cell
protein kinase
tyrosine kinase
high grade