Cook and Move for Your Life, an eHealth intervention for women with breast cancer.
Heather GreenleeEileen Rillamas-SunRachel L YungSofia CobosSidney M DonzellaYuhan HuangLiza SchattenkerkKatherine UelandMatthew VanDorenSamantha A MyersGino GarciaTheresa KingMargarita Santiago-TorresChongzhi DiNeelendu DeyKatherine A GuthrieNancy E DavidsonPublished in: NPJ breast cancer (2024)
We tested the feasibility and preliminary efficacy of an online diet and physical activity program for women with early-stage breast cancer who had completed surgery, chemotherapy, and radiation therapy (ongoing endocrine therapy allowed). Participants with low fruit and vegetable (F/V) consumption and/or low moderate-to-vigorous physical activity (MVPA) levels were randomized to one of two doses - low (one Zoom group session) or high (12 Zoom group sessions) - of an online lifestyle program with the goal of improving F/V intake and MVPA. All participants received eHealth communications (text messages, study website access), a Fitbit, and a WiFi-enabled scale. Primary objectives evaluated feasibility. Secondary objectives compared the 6-month change in F/V intake and MVPA between the two dose groups. Seventy-four women (mean age = 58.4 years; 87% non-Hispanic White; mean time since diagnosis = 4.6 years) were accrued. Among women in the low dose group, 94% attended the single session; among women in the high dose group, 84% attended at least 8 of the 12 sessions. Retention at 6 months was 93%. High relative to low dose participants consumed 1.5 more servings/day of F/V at 6 months (P = 0.007) but MVPA levels did not differ between groups. We successfully implemented an online lifestyle program for early-stage breast cancer survivors. The high dose intervention demonstrated preliminary efficacy in improving F/V consumption in early-stage breast cancer survivors. Future trials can test the intervention in a larger and more diverse population of breast cancer survivors.
Keyphrases
- physical activity
- high dose
- early stage
- low dose
- polycystic ovary syndrome
- randomized controlled trial
- radiation therapy
- stem cell transplantation
- quality improvement
- high intensity
- weight loss
- pregnancy outcomes
- body mass index
- breast cancer risk
- sentinel lymph node
- metabolic syndrome
- cervical cancer screening
- minimally invasive
- double blind
- cardiovascular disease
- placebo controlled
- stem cells
- open label
- type diabetes
- pregnant women
- smoking cessation
- cell therapy
- skeletal muscle
- coronary artery disease
- phase iii
- mesenchymal stem cells
- bone marrow
- radiation induced
- depressive symptoms
- african american
- neoadjuvant chemotherapy
- replacement therapy