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Analgesic effectiveness, pharmacokinetics, and safety of a paracetamol/ibuprofen fixed-dose combination in children undergoing adenotonsillectomy: A randomized, single-blind, parallel group trial.

Rebecca PlayneBrian Joseph AndersonChristopher M A FramptonIoana StanescuHartley C Atkinson
Published in: Paediatric anaesthesia (2018)
The shallow dose-response relationship and good tolerability of the fixed-dose combination over an extended study period supports the utility of both doses of the fixed-dose combination in the home setting.
Keyphrases
  • randomized controlled trial
  • healthcare
  • obstructive sleep apnea
  • systematic review
  • young adults
  • study protocol
  • open label
  • anti inflammatory
  • anti inflammatory drugs