Extensive analysis of mitochondrial DNA quantity and sequence variation in human cumulus cells and assisted reproduction outcomes.
Kishlay KumarMarta VenturasDaniel J NeedlemanCatherine RacowskyDagan WellsPublished in: Human reproduction (Oxford, England) (2021)
This study was funded by National Institutes of Health grant 5R01HD092550-02. D.J.N. and C.R. co-hold patent US20150346100A1 and D.J.N. holds US20170039415A1, both for metabolic imaging methods. D.W. receives support from the NIHR Oxford Biomedical Research Centre. The remaining authors have no conflicts of interest to declare.
Keyphrases
- mitochondrial dna
- copy number
- induced apoptosis
- endothelial cells
- public health
- cell cycle arrest
- high resolution
- mental health
- quality improvement
- health information
- induced pluripotent stem cells
- gene expression
- oxidative stress
- metabolic syndrome
- pluripotent stem cells
- photodynamic therapy
- signaling pathway
- skeletal muscle
- risk assessment
- cell proliferation
- cell death
- health promotion
- human health
- climate change