Tolerability of overnight rotigotine transdermal patch combined with intrajejunal levodopa infusion at 1 year: a 24-h treatment option in Parkinson's disease.

Norlinah Mohamed IbrahimValentina LetaKatarina RukavinaMiriam ParryJenny Ann NatividadVinod MettaGuy Chung-FayeK Ray Chaudhuri

Published in: Journal of neural transmission (Vienna, Austria : 1996) (2022)

Combination of intrajejunal levodopa infusion with overnight rotigotine transdermal patch is well tolerated and extend the beneficial effects of infusion with excellent tolerability; and also improved aspects of mood and apathy sustained at 12 months in advanced Parkinson's disease.

Keyphrases

low dose
parkinson disease
open label
deep brain stimulation
double blind
randomized controlled trial
physical activity
sleep quality
study protocol
combination therapy
replacement therapy