CDX2 dose-dependently influences the gene regulatory network underlying human extraembryonic mesoderm development.

Emily A Bulger Todd C McDevitt Benoit G Bruneau

Published in: bioRxiv : the preprint server for biology (2024)

Using 2D human gastruloids, CDX2 is shown to dose-dependently influence genes related to tissue permeability, cell-cell adhesions, and cytoskeletal architecture during extraembryonic mesoderm development.

Keyphrases

pluripotent stem cells
endothelial cells
single cell
cell therapy
induced pluripotent stem cells
stem cells
bone marrow