Epigenome-Wide DNA Methylation Association Analysis Identified Novel Loci in Peripheral Cells for Alcohol Consumption Among European American Male Veterans.
Ke XuJanitza L Montalvo-OrtizXinyu ZhangSteven M SouthwickJohn H KrystalRobert H PietrzakJoshua C GrayPublished in: Alcoholism, clinical and experimental research (2019)
We identified novel DNA methylation sites associated with alcohol consumption. Results may shed light on peripheral mechanisms of alcohol consumption on adverse health outcomes among heavy drinkers.
Keyphrases
- alcohol consumption
- dna methylation
- genome wide
- gene expression
- induced apoptosis
- public health
- healthcare
- cell cycle arrest
- chemotherapy induced
- mental health
- copy number
- emergency department
- oxidative stress
- endoplasmic reticulum stress
- cell death
- risk assessment
- signaling pathway
- cell proliferation
- social media
- electronic health record