Analysis of Pseudomonas aeruginosa transcription in an ex vivo cystic fibrosis sputum model identifies metal restriction as a gene expression stimulus.
Samuel L NeffGeorgia DoingTaylor E ReiterThomas H HamptonCasey S GreeneDeborah Ann HoganPublished in: bioRxiv : the preprint server for biology (2023)
transcription in CF may benefit from the use of an expectorated sputum model or modified forms of ASM supplemented with metals.
Keyphrases
- cystic fibrosis
- pseudomonas aeruginosa
- gene expression
- lung function
- biofilm formation
- transcription factor
- dna methylation
- acinetobacter baumannii
- genome wide
- pulmonary tuberculosis
- mycobacterium tuberculosis
- chronic obstructive pulmonary disease
- health risk
- air pollution
- climate change
- staphylococcus aureus
- health risk assessment