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Metformin-Treatment Option for Social Impairment? An Open Clinical Trial to Elucidate the Effects of Metformin Treatment on Steroid Hormones and Social Behavior.

Benedikt Andreas GasserJohann KurzSamuel BuerkiMarkus Mohaupt
Published in: Life (Basel, Switzerland) (2022)
It is likely that due to different pathophysiological mechanisms such as an effect on the respiratory chain in mitochondria or via AMP-activated protein kinase, a general alteration of steroid hormone levels can be detected prior to post treatment. The encompassing measurement of steroid hormones shall give hints concerning the involvement of specific cascades yielding potential pharmacological targets for future research.
Keyphrases
  • clinical trial
  • protein kinase
  • healthcare
  • mental health
  • randomized controlled trial
  • climate change
  • study protocol
  • reactive oxygen species
  • smoking cessation
  • double blind
  • endoplasmic reticulum